Multicenter evaluation of a semiautomated, standardized assay for detection of hepatitis B virus DNA in blood donations.
نویسندگان
چکیده
We evaluated the COBAS Ampliscreen hepatitis B virus (HBV) test using standards, seroconversion panels, consecutive donations, and samples from patients with abnormal alanine aminotransferase and chronic hepatitis C. Specificity was 100% and sensitivity was 20 IU/ml. In seroconversion panels, HBV DNA was detected up to 4 to 18 days before HBsAg, suggesting that this assay is useful in shortening the infectious window phase.
منابع مشابه
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 43 6 شماره
صفحات -
تاریخ انتشار 2005